Contact Us

Hybrid PDLLA + HA Collagen-Stimulating Eye Rejuvenation Treatment in Singapore

In the pursuit of brighter, more youthful-looking eyes, the under-eye area often proves to be one of the most challenging to treat. Due to its thin and delicate skin, this region is prone to early signs of ageing such as fine lines, wrinkles, dark circles, and skin laxity — often worsened by sun exposure, fatigue, and collagen loss.

This advanced Korean-developed injectable treatment combines hyaluronic acid (HA) with poly-D,L-lactic acid (PDLLA) — a hybrid formulation specifically engineered for delicate areas like the tear trough. It offers both immediate hydration and long-term collagen regeneration, making it a suitable non-surgical solution for under-eye rejuvenation.

Key components:

  • Hyaluronic acid (HA): A hydrating molecule that instantly plumps and smooths the skin, improving moisture levels and softening fine lines.
  • Poly-D,L-lactic acid (PDLLA): A biocompatible collagen stimulator that encourages natural collagen production. The PDLLA microparticles are finely tuned for safety in sensitive regions, reducing the risk of clumping or granulomas.

This next-generation hybrid injectable from Korea is particularly effective for:

  • Dark circles caused by skin thinning
  • Fine lines and crepey under-eye texture
  • Loss of skin firmness and elasticity

By harnessing the synergistic effects of HA and PDLLA, this treatment delivers progressive and natural-looking improvements in skin quality, with results that continue to evolve over several months.

Learn more about full-face applications of this injectable collagen skinbooster here.

Improvement of Under-Eye Fine Lines and Wrinkles

Fine lines and wrinkles are some of the earliest signs of ageing to appear in the delicate under-eye region. This hybrid PDLLA + HA injectable addresses these concerns through a two-pronged approach.

  • The hyaluronic acid (HA) component delivers immediate hydration, helping to plump up the skin and smooth out fine lines.
  • Over time, poly-D,L-lactic acid (PDLLA) stimulates collagen production within the dermis. This gradual strengthening of the skin’s structural matrix leads to sustained improvement in skin firmness, resulting in a visibly smoother and younger-looking under-eye area.

This progressive rejuvenation makes the treatment ideal for patients seeking subtle, natural improvements without the risk of an overfilled or puffy appearance.

Enhanced Skin Texture and Elasticity

As collagen levels gradually increase due to PDLLA activation, the skin around the eyes becomes firmer, more resilient, and more youthful in appearance. Improved skin elasticity helps to reduce under-eye crepiness and sagging, while enhanced dermal density contributes to smoother texture overall.

The HA component complements this by delivering deep hydration, giving the skin a fresher, healthier glow. The result is an improvement not just in wrinkles, but in overall skin quality.

Subtle Volume Support for Hollow Tear Troughs

With age, the under-eye area can appear more tired or sunken due to skin thinning, collagen loss, and mild volume depletion. While traditional tear trough fillers remain the gold standard for significant volume restoration, this hybrid PDLLA + HA collagen booster can offer subtle improvement in patients with mild hollowing.

  • The hyaluronic acid (HA) component provides hydration and gentle plumping, helping to smooth fine creases and reduce the shadowing effect that contributes to a tired appearance.
  • The poly-D, L-lactic acid (PDLLA) component works gradually to stimulate collagen production, which helps to strengthen the skin and enhance dermal support over time.

This treatment is not a replacement for tear trough fillers, but it is well-suited for patients looking to improve skin quality, mild hollowness, and early signs of fatigue — all without the risk of puffiness or overcorrection.

Schedule your facelift consultation

Visit Our Clinic

Medical Aesthetic Clinic Singapore

The Hybrid PDLLA + HA Under-Eye Treatment Process

This collagen-stimulating eye rejuvenation procedure involves a series of targeted injections designed to improve skin quality, hydration, and elasticity in the delicate under-eye region. Dr Edwin offers two different techniques for administering this hybrid PDLLA + HA injectable, each tailored to individual patient needs, skin thickness, and treatment goals.

Option 1: Cannula-Based Injection Technique

This method involves delivering the injectable using a blunt-tipped microcannula. It is ideal for patients seeking minimal downtime, as the cannula reduces the risk of bruising and swelling while allowing precise placement of the solution beneath the skin.

Benefits of the cannula technique:

  • Lower risk of post-treatment bruising
  • Precise placement of the injectable along the tear trough
  • Smooth, even distribution with minimal trauma to surrounding tissues
  • Preferred for deeper placement in patients with mild under-eye hollowness and skin laxity

Option 2: Dermashine Pro Micro-Injection System

The Dermashine Pro system uses ultra-fine needles to administer the hybrid PDLLA + HA injectable across the superficial dermis. This method is particularly well-suited for patients with crepey skin, fine lines, or those looking to improve overall skin texture and hydration in the under-eye area.

Compared to manual injections, the Dermashine Pro offers several advantages:

  • Reduced pain and discomfort due to consistent needle speed and depth
  • Greater precision, ensuring even distribution of the injectable solution
  • Controlled injection depth, minimising the risk of product wastage or uneven results
  • Enhanced ability to treat a wider surface area uniformly, especially beneficial for patients seeking overall rejuvenation

It is especially effective for patients who prefer a less invasive experience while achieving smoother skin and enhanced hydration.

Watch a demonstration of this treatment below

Step-by-Step Overview

1. Consultation
A detailed consultation with Dr Edwin will be conducted to assess skin condition, degree of hollowing, and suitability for the treatment. Based on individual needs, the most appropriate technique — cannula or microinjection — will be recommended.

2. Preparation
The under-eye area will be thoroughly cleansed, and a topical anaesthetic will be applied to ensure comfort. For cannula procedures, precise entry points will be marked.

3. Injection

  • Cannula Method: A microcannula is inserted through a small entry point to deliver the hybrid PDLLA + HA injectable beneath the skin.
  • Dermashine Pro: The injectable is deposited across the skin’s surface via ultra-fine needles, ensuring even and consistent coverage.

4. Post-Treatment Care
Some mild redness or swelling may occur, typically resolving within a few hours to a few days. Patients will receive detailed aftercare instructions to support healing and optimise results.

How Often Should Hybrid PDLLA + HA Under-Eye Collagen Booster Treatments Be Done?

Treatment frequency depends on individual skin condition, degree of ageing, and desired results. Most patients benefit from an initial induction phase followed by periodic maintenance sessions to sustain long-term skin improvements.

Initial Treatment Phase

A series of 3 to 5 treatment sessions is typically recommended, spaced approximately 3 to 4 weeks apart. This structured approach supports ongoing collagen stimulation while replenishing skin hydration in the delicate under-eye area. Over this period, patients can expect gradual improvements in fine lines, skin elasticity, and texture.

The hybrid formulation of poly-D,L-lactic acid (PDLLA) and hyaluronic acid (HA) works synergistically to enhance both short-term skin hydration and long-term dermal remodeling.

Maintenance Phase

Following the initial course, maintenance treatments are usually recommended every 6 to 9 months to prolong and enhance the results. These touch-up sessions continue to support collagen renewal and help maintain overall skin quality.

Depending on individual factors such as age, lifestyle, and skin metabolism, some patients may benefit from more frequent maintenance intervals.

Longevity of Results

Results from hybrid PDLLA + HA treatments may last beyond one year in many patients. With proper aftercare and ongoing maintenance, skin around the eyes can remain smoother, firmer, and more youthful-looking over time.

Expected Results and Timeline

Patients can expect a progressive improvement in the under-eye area as the hybrid PDLLA + HA collagen booster works in stages. Results unfold gradually and are most noticeable over a series of treatments.

Immediately after each session:

  • Skin may appear slightly plumper and more hydrated
  • Mild redness or swelling may be observed, typically resolving within 1–2 days

After 2 to 3 sessions:

  • Fine lines and crepiness begin to soften
  • Dark circles caused by thinning skin may appear lighter
  • The under-eye area looks smoother and more refreshed

By 2 to 3 months:

  • Continued collagen production leads to firmer, more elastic skin
  • Improvements in skin quality become more long-lasting and noticeable
  • Overall eye area looks less tired, with a rejuvenated and healthier appearance

As collagen stimulation continues post-treatment, results can continue to improve for several months, especially when paired with maintenance sessions every 6 to 9 months.

Is This Hybrid PDLLA + HA Under-Eye Collagen Booster Suitable for Me?

This treatment is ideal for patients who experience early signs of ageing or tiredness around the eyes but do not require full-volume correction with tear trough fillers.

Suitable for:

  • Fine lines or crepey under-eye texture
  • Mild dark circles from skin thinning or poor circulation
  • Mild under-eye hollowing not severe enough to require fillers
  • Patients seeking overall skin improvement with a gradual, natural effect
  • Those who want a collagen-boosting alternative to skinboosters or polynucleotide injectables

It is especially beneficial for younger patients, or those who wish to prevent further ageing changes before more invasive interventions are required.

Why Choose Dr Edwin for Under-Eye Rejuvenation?

Under-eye treatments require precision, experience, and a deep understanding of facial anatomy. Dr Edwin Lim has extensive experience in tailoring injectable treatments based on each patient’s skin condition, ageing severity, and anatomical structure.

  • Offers both cannula-based and Dermashine Pro microinjection techniques for precise delivery
  • Uses only clinically backed injectables with strong safety profiles
  • Customises each treatment plan for natural-looking, gradual improvement
  • Committed to doctor-performed procedures for safety and optimal outcomes

At Edwin Lim Medical Aesthetic Clinic, your treatment is not just about aesthetics—it’s about achieving healthy, long-term skin rejuvenation with scientifically proven methods.

Frequently Asked Questions

Yes, Juvelook is formulated with finely calibrated PDLLA microparticles designed for safe use in thin, delicate areas like the tear trough. The risk of lumpiness or granulomas is low when administered properly, and Dr Edwin uses precise techniques to ensure both safety and efficacy.

With Juvelook, patients typically notice improved skin hydration and plumpness within the first week. Collagen stimulation begins gradually, with visible improvements in fine lines, texture, and elasticity developing over the next 6 to 12 weeks. Results continue to enhance with each session and may peak several months after the final treatment.

Juvelook is suitable for adults of various age groups who are looking to improve fine lines, mild dark circles, or crepey under-eye skin. Younger patients in their 20s and 30s may use it preventatively, while older individuals may benefit from its regenerative collagen-stimulating effects. Suitability will depend on skin thickness, degree of volume loss, and overall eye structure.

Both treatments aim to improve under-eye skin quality, but they work differently. Salmon DNA-based injectables (commonly known as 婴儿针 or Rejuran Eye) focus on cellular repair and wound healing. Juvelook, on the other hand, stimulates collagen while also hydrating the skin, offering a longer-lasting structural benefit. In some cases, both treatments may be combined for synergistic results.

Dr Edwin Lim

MBBS (Singapore), MRCS (Edinburgh), PgDip Practical Dermatology (Cardiff), MSc Practical Dermatology (Cardiff), Diploma in Aesthetic Medicine, (AAAM), Accredited by the Aesthetic Dermatology Educational Group (ADEG)
Devoted to Beauty
Achieved through Science
This article has been medically reviewed by Dr Edwin Lim
Dr Edwin has a fond interest in Aesthetic injectable procedures such as Fillers, Skinboosters and Botox. He is passionate about enhancing one's beauty by delivering natural looking results with well placed injections.

The care you deserve

The Results You Want

Achieve your goals with Dr Edwin Lim
+65 9637 2218
© 2025 Edwin Lim Medical Aesthetic Clinic