Due to Health Sciences Authority (HSA) advertising regulations, we are unable to mention the specific brand name of our polynucleotide scar treatment. However, we use a premium polynucleotide formulation from Korea—commonly identified online and on social media as the "blue box," or associated with "salmon sperm" or "salmon DNA."
Polynucleotide Acne Scar Treatment is a procedure designed to improve the appearance of acne scars. It uses polynucleotides (PN), DNA fragments that support the skin’s natural repair and regeneration processes.
This treatment works by addressing the underlying issues of damaged skin tissue caused by acne, focusing on promoting cellular repair and stimulating collagen production. Polynucleotides are biocompatible and work beneath the skin’s surface to assist in tissue renewal, helping to restore a smoother skin texture.
Polynucleotide Acne Scar Treatment can address a range of scar types, making it suitable for different severities and conditions. The approach targets the structural layers of the skin, supporting long-term improvements in texture and elasticity rather than just surface-level changes.
The treatment offers polynucleotides formulated to aid in skin repair, making it an option for those looking to improve acne scars and skin texture over time.
Acne scars form as a result of damage to the skin tissue caused by inflammation from acne. When the skin becomes inflamed, the body initiates a healing process to repair the affected areas by producing collagen, a protein essential for maintaining skin structure and elasticity.
If the body produces too little collagen during this process, it can lead to depressed or pitted scars, as the skin lacks sufficient support to restore a smooth surface. Conversely, excessive collagen production may result in raised scars (hypertrophic scars and keloids). Factors such as the severity of acne, the depth of inflammation, and the individual’s skin type can all influence the likelihood and appearance of scars.
This imbalance in collagen production is the primary reason why acne scars develop, leading to uneven skin texture and permanent changes in the skin’s appearance. Identifying the type and cause of scars is important for determining the most appropriate treatment approach.
Polynucleotide Acne Scar Treatment focuses on repairing skin damage caused by acne, making it effective for treating different types of scars. These include:
Polynucleotide Acne Scar Treatment works by targeting the skin's regenerative processes to repair and improve the appearance of acne scars. By leveraging the properties of polynucleotides, this treatment promotes healing, enhances skin repair, and boosts collagen production, addressing the root causes of acne scars for smoother and healthier skin.
Polynucleotides, extracted from salmon DNA, act as a biological scaffold within the skin. This scaffold supports the growth of new skin cells and encourages the regeneration of damaged tissue. The biocompatibility of polynucleotides ensures they integrate well into the skin, aiding in the restoration of areas affected by acne scars.
Polynucleotides stimulate the release of growth factors, which play a crucial role in skin repair and renewal. These growth factors activate the skin's natural healing processes, allowing damaged tissue to recover more effectively and reducing the appearance of scars over time.
Collagen is a vital protein that provides skin with its strength, elasticity, and structural support. Polynucleotide Acne Scar Treatment stimulates the production of collagen, which is crucial for repairing and rejuvenating skin damaged by acne scars.
By boosting collagen levels, this treatment helps fill in and smoothen depressed scars, restoring the skin's firmness and resilience. Over time, the increased collagen production enhances the skin's structural integrity, leading to a more even texture and a healthier overall appearance. This regeneration process not only addresses existing scars but also promotes long-term skin improvement.
Polynucleotide Acne Scar Treatment provides a structured and targeted approach to improving acne scars. This minimally invasive procedure is designed to enhance skin healing and rejuvenation effectively and safely.
Prior to the treatment, a topical anesthetic such as numbing cream is applied to reduce discomfort. For patients requiring additional pain management, nerve block injections may also be used. These measures ensure that the procedure is as comfortable as possible, especially for individuals with sensitive skin or larger treatment areas.
The treatment involves precise injections of polynucleotides directly beneath the acne scars using a fine needle. These injections are carefully administered to target the underlying damage caused by acne, promoting tissue repair and regeneration. Post-treatment, small bumps will form at the injection sites.
These bumps are a normal part of the process and indicate the presence of the treatment solution under the skin, where it begins its work to heal and smooth scars. These bumps will subside within 5 to 7 days.
Following the procedure, patients should use an intensive recovery cream to support the skin's healing process. Gentle massaging of the treated areas over the next few days is recommended to aid in the even distribution of the polynucleotides and to enhance their effectiveness.
Temporary side effects such as minor swelling, bruising, or needle marks may occur but typically subside within 5 to 7 days. Patients are advised to follow all post-treatment care instructions provided by the clinic to achieve the good results and minimize downtime.
Subcision can be performed alongside Polynucleotide Acne Scar Treatment to address deeper or more pronounced acne scars. This combined approach is effective for treating scars tethered to the underlying skin layers.
Subcision works by using a fine needle to break the fibrous bands that pull the skin down, creating the appearance of depressed scars. Once these bands are released, the skin can naturally lift, reducing the depth of the scar.
Following subcision, polynucleotides are injected into the base of the treated scar. These injections promote collagen production and accelerate the healing process. The polynucleotides act as a scaffold, supporting tissue regeneration and helping to rebuild smoother and more even skin over time.
This combined treatment not only targets the structural causes of deep acne scars but also enhances the skin’s natural repair mechanisms, resulting in improvements in scar appearance and skin texture.
The number of treatments required for Polynucleotide Acne Scar Treatment varies based on the severity, type, and extent of the acne scars. Each session is tailored to the patient’s unique skin condition, ensuring optimal results.
Depending on the number of scars, in some cases, multiple syringes (1ml each) are needed during a single session to adequately address the affected areas. Generally, a series of 3 to 5 treatment sessions is recommended, spaced 4 weeks apart.
Results may vary from individual to individual, influenced by factors such as the depth and severity of the scars, the skin's natural regenerative capacity, and overall health. A consultation with your doctor allows for a thorough assessment of your skin condition. Based on this evaluation, a personalized treatment plan will be created to determine the optimal number of sessions needed to achieve smoother and better skin.
For patients with different types of acne scars, a combination treatment approach can deliver more effective results. By targeting scars of varying types and depths, this method enhances overall skin texture and appearance.
The CO2 Fractional Resurfacing Laser works alongside polynucleotide treatments by focusing on superficial scars and textural irregularities. By creating precise micro-injuries in the skin, the laser stimulates new collagen production and enhances the skin's surface, reducing the appearance of acne scars.
Sylfirm X, also known as 黄金微针, is a valuable addition to combination treatments. It addresses both the color and structural components of acne scars, offering a comprehensive solution for improving their appearance.
Using radiofrequency microneedling, Sylfirm X targets redness and discoloration in scars, reducing vascular-related pigmentation while simultaneously stimulating collagen production. This dual-action treatment not only enhances the colour and appearance of scars but also improves the overall skin texture.
Polynucleotide Acne Scar Treatment is a safe and effective procedure when performed by an experienced doctor. This treatment uses biocompatible polynucleotides derived from salmon DNA, which are well-tolerated by most individuals.
Common Side Effects of Polynucleotide Acne Scar Treatment
Rare Side Effects of Polynucleotide Acne Scar Treatment
Polynucleotide (PN) Skin Rejuvenation Therapy is widely regarded as a safe and well-tolerated treatment when performed by trained medical professionals. At our Singapore clinic, patient safety, comfort, and optimal outcomes are prioritised at every stage of your PN therapy journey.
The polynucleotides used in these treatments are derived from salmon DNA and undergo advanced purification processes to ensure high biocompatibility with human skin. These formulations have been clinically validated for medical aesthetic use, demonstrating a very low risk of allergic reactions or adverse effects.
For more insights into the clinical science behind polynucleotide skin therapies, you may refer to this clinical review on PN therapy safety and efficacy.
While PN therapy is associated with minimal downtime, mild and temporary side effects may occur, including:
These side effects are self-limiting and part of the skin’s natural healing response. To minimise downtime and maximise comfort, we utilise fine-gauge needles, optimised injection techniques, and provide tailored post-care protocols.
To ensure a smooth recovery and enhance the regenerative effects of your skin booster treatment, we recommend:
Should you experience any unexpected symptoms following your Polynucleotide (PN) injection, our clinic team is readily available to provide support and guidance throughout your recovery process.through the recovery process.
When considering Polynucleotide (PN) Skin Rejuvenation Therapy, it is important to select a trusted and experienced medical aesthetic clinic to ensure your safety, treatment quality, and overall satisfaction.
Here are important factors to consider when choosing the best clinic for PN skin rejuvenation in Singapore:
Always ensure that PN injections are performed by qualified medical doctors. An experienced doctor understands facial anatomy, regenerative mechanisms, and safe injection techniques — all essential for achieving optimal, natural-looking results.
Select a clinic with extensive experience in regenerative skin treatments, particularly in polynucleotide-based therapies. Clinics familiar with collagen stimulation and skin repair procedures can better personalise your treatment plan to suit your specific concerns.
The best outcomes are achieved when treatment plans are tailored to the individual. Look for clinics that offer thorough consultations to assess your skin condition, medical history, and lifestyle factors before recommending a PN therapy approach.
A reputable clinic will clearly explain the expected outcomes, downtime, possible side effects, and aftercare instructions. Comprehensive post-treatment support is important to ensure a smooth recovery and maximise the regenerative benefits of PN therapy.
Clinics with strong patient feedback, visible before-and-after results, and a consistent track record in regenerative skin treatments provide greater confidence in the quality of care and results you can expect.
If you are considering Polynucleotide (PN) Skin Rejuvenation Therapy to improve your skin’s hydration, elasticity, and overall radiance, our clinic is here to help. We provide doctor-led, personalised treatment plans designed to support your skin’s natural regeneration safely and effectively.
Schedule a consultation with our experienced medical team today to find out how PN therapy can be tailored to your unique skin goals.
Let us guide you towards achieving firmer, healthier, and more radiant skin — naturally.
Polynucleotide therapy involves the injection of biocompatible DNA fragments to stimulate the skin’s natural regenerative processes. It promotes collagen production, tissue repair, and scar remodelling, making it an effective option for improving acne scars.
Polynucleotide injectables such as Rejuran S (Scar) are commonly used to target depressed or uneven skin surfaces.
Individuals with atrophic acne scars, such as rolling scars, boxcar scars, or mild ice-pick scars, are suitable candidates for polynucleotide-based treatments. Patients seeking a minimally invasive approach to improve skin texture, scar depth, and resilience may benefit from therapies involving Rejuran S.
After treatment, most patients experience mild swelling, redness, or small bumps at the injection sites. These effects are typically temporary and resolve within five to seven days.
Biocompatible formulations such as Rejuran S are generally well tolerated, and patients are usually able to resume normal daily activities shortly after the procedure.
Most patients require three to five sessions, spaced approximately four weeks apart, to achieve optimal improvements in scar appearance. Depending on the severity of scarring and individual skin response, adjustments to the treatment protocol using polynucleotide products like Rejuran Scar may be recommended for the best outcomes.
Polynucleotide-based therapies are considered safe when performed by trained medical professionals. Products such as Rejuran S, Plinest, and Nucleofill undergo advanced purification to ensure high biocompatibility, reducing the risk of allergic reactions and supporting safe, natural skin healing and tissue regeneration.
Yes, Rejuran S injections can be safely combined with other scar revision techniques to achieve more comprehensive results. Treatments such as subcision, CO₂ fractional resurfacing laser, or radiofrequency microneedling (e.g., Sylfirm X) can be customised alongside Rejuran Scar injections to target different layers of scar tissue and enhance overall skin texture.
After Rejuran Scar, some early improvements may be noticed around three to four weeks after the initial session. However, more significant skin texture improvements typically develop progressively over several months as collagen production increases and tissue remodelling continues.
Treatments involving Rejuran S are designed to provide gradual, natural-looking enhancements over time.
Rejuran injectables are formulated to address specific skin concerns using varying concentrations and consistencies.
Rejuran Healer is commonly used for general skin rejuvenation, aiming to improve hydration, skin texture, and resilience.
Rejuran I is specially formulated with a lighter consistency for delicate areas such as the under-eye region, targeting fine lines and skin thinning.
Rejuran HB (Hydroboost) combines polynucleotides with hyaluronic acid to enhance both skin hydration and tissue repair.
Rejuran S is designed specifically for acne scars, with a higher viscosity to provide structural support to depressed or uneven skin surfaces.
The choice of formulation depends on your skin condition and treatment goals, and will be determined during your personalised consultation.
