Hybrid PDLLA + HA Collagen-Stimulating Eye Rejuvenation Treatment in Singapore

In the pursuit of brighter, more youthful-looking eyes, the under-eye area often proves to be one of the most challenging to treat. Due to its thin and delicate skin, this region is prone to early signs of ageing such as fine lines, wrinkles, dark circles, and skin laxity — often worsened by sun exposure, fatigue, and collagen loss.

This advanced Korean-developed injectable treatment combines hyaluronic acid (HA) with poly-D,L-lactic acid (PDLLA) — a hybrid formulation specifically engineered for delicate areas like the tear trough. It offers both immediate hydration and long-term collagen regeneration, making it a suitable non-surgical solution for under-eye rejuvenation.

Key components:

Hyaluronic acid (HA): A hydrating molecule that instantly plumps and smooths the skin, improving moisture levels and softening fine lines.
Poly-D,L-lactic acid (PDLLA): A biocompatible collagen stimulator that encourages natural collagen production. The PDLLA microparticles are finely tuned for safety in sensitive regions, reducing the risk of clumping or granulomas.

This next-generation hybrid injectable from Korea is particularly effective for:

Dark circles caused by skin thinning
Fine lines and crepey under-eye texture
Loss of skin firmness and elasticity

By harnessing the synergistic effects of HA and PDLLA, this treatment delivers progressive and natural-looking improvements in skin quality, with results that continue to evolve over several months.

Learn more about full-face applications of this injectable collagen skinbooster here.

Benefits of Hybrid PDLLA + HA Under-Eye Collagen Booster

This next-generation Korean injectable offers a comprehensive solution for under-eye rejuvenation. By combining hyaluronic acid (HA) and poly-D,L-lactic acid (PDLLA) in one treatment, it provides both immediate skin hydration and long-term collagen stimulation—without the heaviness or swelling commonly associated with traditional dermal fillers.

Its safety profile, especially in delicate areas such as the tear trough, and ability to deliver progressive yet natural-looking results make it an ideal option for patients seeking to restore brightness and smoothness under the eyes without undergoing surgery.

Key benefits of this hybrid injectable:

Minimises the risk of lumpiness or granulomas due to optimised microparticle size
Hydrates and plumps the under-eye region for a refreshed appearance
Smooths fine lines and crepey texture
Stimulates collagen to improve skin thickness and resilience
Helps reduce the appearance of hollowing and tired-looking eyes
Gradually enhances skin elasticity and firmness over time

Targeting Dark Circles and Eye Rejuvenation

Dark circles under the eyes are typically caused by a combination of volume loss, skin thinning, pigmentation, and impaired circulation. This injectable is specifically formulated to address these factors through a synergistic mechanism.

Hyaluronic acid (HA): Provides immediate hydration and volumisation. By replenishing moisture and filling hollow tear troughs, HA helps to reduce shadowing that contributes to the appearance of dark circles. It also improves overall skin texture and elasticity.
Poly-D,L-lactic acid (PDLLA): Acts as a biostimulatory agent that activates fibroblasts to generate new collagen over time. In addition to enhancing skin firmness, PDLLA promotes angiogenesis—new blood vessel formation—which may improve local circulation and help reduce the bluish discoloration associated with vascular dark circles.

This dual-technology approach not only improves the appearance of the under-eye region but also supports healthier, more resilient skin over the long term.

Improvement of Under-Eye Fine Lines and Wrinkles

Fine lines and wrinkles are some of the earliest signs of ageing to appear in the delicate under-eye region. This hybrid PDLLA + HA injectable addresses these concerns through a two-pronged approach.

The hyaluronic acid (HA) component delivers immediate hydration, helping to plump up the skin and smooth out fine lines.
Over time, poly-D,L-lactic acid (PDLLA) stimulates collagen production within the dermis. This gradual strengthening of the skin’s structural matrix leads to sustained improvement in skin firmness, resulting in a visibly smoother and younger-looking under-eye area.

This progressive rejuvenation makes the treatment ideal for patients seeking subtle, natural improvements without the risk of an overfilled or puffy appearance.

Enhanced Skin Texture and Elasticity

As collagen levels gradually increase due to PDLLA activation, the skin around the eyes becomes firmer, more resilient, and more youthful in appearance. Improved skin elasticity helps to reduce under-eye crepiness and sagging, while enhanced dermal density contributes to smoother texture overall.

The HA component complements this by delivering deep hydration, giving the skin a fresher, healthier glow. The result is an improvement not just in wrinkles, but in overall skin quality.

Subtle Volume Support for Hollow Tear Troughs

With age, the under-eye area can appear more tired or sunken due to skin thinning, collagen loss, and mild volume depletion. While traditional tear trough fillers remain the gold standard for significant volume restoration, this hybrid PDLLA + HA collagen booster can offer subtle improvement in patients with mild hollowing.

The hyaluronic acid (HA) component provides hydration and gentle plumping, helping to smooth fine creases and reduce the shadowing effect that contributes to a tired appearance.
The poly-D,L-lactic acid (PDLLA) component works gradually to stimulate collagen production, which helps to strengthen the skin and enhance dermal support over time.

This treatment is not a replacement for tear trough fillers, but it is well-suited for patients looking to improve skin quality, mild hollowness, and early signs of fatigue — all without the risk of puffiness or overcorrection.

The Hybrid PDLLA + HA Under-Eye Treatment Process

This collagen-stimulating eye rejuvenation procedure involves a series of targeted injections designed to improve skin quality, hydration, and elasticity in the delicate under-eye region. Dr Edwin offers two different techniques for administering this hybrid PDLLA + HA injectable, each tailored to individual patient needs, skin thickness, and treatment goals.

Option 1: Cannula-Based Injection Technique

This method involves delivering the injectable using a blunt-tipped microcannula. It is ideal for patients seeking minimal downtime, as the cannula reduces the risk of bruising and swelling while allowing precise placement of the solution beneath the skin.

Benefits of the cannula technique:

Lower risk of post-treatment bruising
Precise placement of the injectable along the tear trough
Smooth, even distribution with minimal trauma to surrounding tissues
Preferred for deeper placement in patients with mild under-eye hollowness and skin laxity

Option 2: Dermashine Pro Micro-Injection System

The Dermashine Pro system uses ultra-fine needles to administer the hybrid PDLLA + HA injectable across the superficial dermis. This method is particularly well-suited for patients with crepey skin, fine lines, or those looking to improve overall skin texture and hydration in the under-eye area.

Compared to manual injections, the Dermashine Pro offers several advantages:

Reduced pain and discomfort due to consistent needle speed and depth
Greater precision, ensuring even distribution of the injectable solution
Controlled injection depth, minimising the risk of product wastage or uneven results
Enhanced ability to treat a wider surface area uniformly, especially beneficial for patients seeking overall rejuvenation

It is especially effective for patients who prefer a less invasive experience while achieving smoother skin and enhanced hydration.

Watch a demonstration of this treatment below

Step-by-Step Overview

1. Consultation
A detailed consultation with Dr Edwin will be conducted to assess skin condition, degree of hollowing, and suitability for the treatment. Based on individual needs, the most appropriate technique — cannula or microinjection — will be recommended.

2. Preparation
The under-eye area will be thoroughly cleansed, and a topical anaesthetic will be applied to ensure comfort. For cannula procedures, precise entry points will be marked.

3. Injection

Cannula Method: A microcannula is inserted through a small entry point to deliver the hybrid PDLLA + HA injectable beneath the skin.
Dermashine Pro: The injectable is deposited across the skin’s surface via ultra-fine needles, ensuring even and consistent coverage.

4. Post-Treatment Care
Some mild redness or swelling may occur, typically resolving within a few hours to a few days. Patients will receive detailed aftercare instructions to support healing and optimise results.

How Often Should Hybrid PDLLA + HA Under-Eye Collagen Booster Treatments Be Done?

Treatment frequency depends on individual skin condition, degree of ageing, and desired results. Most patients benefit from an initial induction phase followed by periodic maintenance sessions to sustain long-term skin improvements.

Initial Treatment Phase

A series of 3 to 5 treatment sessions is typically recommended, spaced approximately 3 to 4 weeks apart. This structured approach supports ongoing collagen stimulation while replenishing skin hydration in the delicate under-eye area. Over this period, patients can expect gradual improvements in fine lines, skin elasticity, and texture.

The hybrid formulation of poly-D,L-lactic acid (PDLLA) and hyaluronic acid (HA) works synergistically to enhance both short-term skin hydration and long-term dermal remodeling.

Maintenance Phase

Following the initial course, maintenance treatments are usually recommended every 6 to 9 months to prolong and enhance the results. These touch-up sessions continue to support collagen renewal and help maintain overall skin quality.

Depending on individual factors such as age, lifestyle, and skin metabolism, some patients may benefit from more frequent maintenance intervals.

Longevity of Results

Results from hybrid PDLLA + HA treatments may last beyond one year in many patients. With proper aftercare and ongoing maintenance, skin around the eyes can remain smoother, firmer, and more youthful-looking over time.

Expected Results and Timeline

Patients can expect a progressive improvement in the under-eye area as the hybrid PDLLA + HA collagen booster works in stages. Results unfold gradually and are most noticeable over a series of treatments.

Immediately after each session:

Skin may appear slightly plumper and more hydrated
Mild redness or swelling may be observed, typically resolving within 1–2 days

After 2 to 3 sessions:

Fine lines and crepiness begin to soften
Dark circles caused by thinning skin may appear lighter
The under-eye area looks smoother and more refreshed

By 2 to 3 months:

Continued collagen production leads to firmer, more elastic skin
Improvements in skin quality become more long-lasting and noticeable
Overall eye area looks less tired, with a rejuvenated and healthier appearance

As collagen stimulation continues post-treatment, results can continue to improve for several months, especially when paired with maintenance sessions every 6 to 9 months.

Is This Hybrid PDLLA + HA Under-Eye Collagen Booster Suitable for Me?

This treatment is ideal for patients who experience early signs of ageing or tiredness around the eyes but do not require full-volume correction with tear trough fillers.

Suitable for:

Fine lines or crepey under-eye texture
Mild dark circles from skin thinning or poor circulation
Mild under-eye hollowing not severe enough to require fillers
Patients seeking overall skin improvement with a gradual, natural effect
Those who want a collagen-boosting alternative to skinboosters or polynucleotide injectables

It is especially beneficial for younger patients, or those who wish to prevent further ageing changes before more invasive interventions are required.

Why Choose Dr Edwin for Under-Eye Rejuvenation?

Under-eye treatments require precision, experience, and a deep understanding of facial anatomy. Dr Edwin Lim has extensive experience in tailoring injectable treatments based on each patient’s skin condition, ageing severity, and anatomical structure.

Offers both cannula-based and Dermashine Pro microinjection techniques for precise delivery
Uses only clinically backed injectables with strong safety profiles
Customises each treatment plan for natural-looking, gradual improvement
Committed to doctor-performed procedures for safety and optimal outcomes

At Edwin Lim Medical Aesthetic Clinic, your treatment is not just about aesthetics—it’s about achieving healthy, long-term skin rejuvenation with scientifically proven methods.

Frequently Asked Questions

What Is This Hybrid Collagen-Stimulating Injectable Made Of?

The injectable used is Juvelook, a Korean formulation that combines hyaluronic acid (HA) and poly-D,L-lactic acid (PDLLA). HA provides immediate hydration and plumping, while PDLLA stimulates your skin’s natural collagen production over time. Together, they help improve elasticity, firmness, and under-eye texture.

How Is This Different From Tear Trough Fillers?

Juvelook is not a volumising filler. While tear trough fillers are intended to restore deeper volume, Juvelook focuses on improving under-eye skin quality. It addresses fine lines, mild hollowness, and dark circles through hydration and collagen stimulation, making it suitable for patients seeking a gradual and natural enhancement.

How Many Sessions Will I Need?

The typical treatment plan for Juvelook includes 3 to 5 sessions spaced 3 to 4 weeks apart. Maintenance treatments are recommended every 6 to 9 months to sustain collagen production and skin improvements. Dr Edwin will personalise your plan based on your skin’s condition and goals.

Is There Downtime After Hybrid Under-Eye Collagen Stimulating Injections?

Downtime after Juvelook is minimal. You may experience mild redness, swelling, or tiny injection marks, which usually subside within 1 to 2 days. When using the cannula method, bruising is less common. If performed with the Dermashine Pro system, temporary pinpoint marks may be visible but resolve quickly.

Is This Collagen-Stimulating Eye Treatment Painful?

Juvelook is well tolerated by most patients. A numbing cream is applied before the procedure. The Dermashine Pro method is typically more comfortable, as it uses ultra-fine needles and delivers the injectable at a controlled depth, resulting in less pain and greater consistency than manual injections.

Can This Be Combined With Other Under-Eye Treatments?

Yes, Juvelook can be combined with other treatments such as Rejuran Eye (e.g. 婴儿针), laser therapy, or skinboosters. Depending on your concerns—whether fine lines, skin laxity, or pigmentation—Dr Edwin may recommend a combination approach for enhanced results.

Is This Injectable Safe for Sensitive Under-Eye Skin?

Yes, Juvelook is formulated with finely calibrated PDLLA microparticles designed for safe use in thin, delicate areas like the tear trough. The risk of lumpiness or granulomas is low when administered properly, and Dr Edwin uses precise techniques to ensure both safety and efficacy.

How Soon Will I See Results From This Treatment?

With Juvelook, patients typically notice improved skin hydration and plumpness within the first week. Collagen stimulation begins gradually, with visible improvements in fine lines, texture, and elasticity developing over the next 6 to 12 weeks. Results continue to enhance with each session and may peak several months after the final treatment.

Is This Under-Eye Injection Suitable for All Ages?

Juvelook is suitable for adults of various age groups who are looking to improve fine lines, mild dark circles, or crepey under-eye skin. Younger patients in their 20s and 30s may use it preventatively, while older individuals may benefit from its regenerative collagen-stimulating effects. Suitability will depend on skin thickness, degree of volume loss, and overall eye structure.

How Does This Compare to Salmon DNA or Polynucleotide Injections?

Both treatments aim to improve under-eye skin quality, but they work differently. Salmon DNA-based injectables (commonly known as 婴儿针 or Rejuran Eye) focus on cellular repair and wound healing. Juvelook, on the other hand, stimulates collagen while also hydrating the skin, offering a longer-lasting structural benefit. In some cases, both treatments may be combined for synergistic results.

Ready to Refresh and Rejuvenate Your Eyes?

Tired-looking eyes can add years to your appearance. Whether you're concerned about dark circles, fine lines, or thinning under-eye skin, this doctor-led collagen-stimulating injectable may help restore a brighter, more youthful look.

Dr Edwin Lim offers personalised under-eye rejuvenation plans using advanced injectable techniques, including cannula or microinjection with the Dermashine Pro system—ensuring optimal safety and natural results.

Book a consultation to find out if this treatment is suitable for your under-eye concerns.