Monthly Archives: September 2019

Hyalase – Dissolving Fillers in Singapore

Hyalase (Hyaluronidase) - Dissolving Dermal Fillers in Singapore

Regret having Fillers injected?

Unhappy with your Filler results?

Unexpected bumps from Fillers?

It is not the end of the world. You do not need to wait 1 to 2 years for the dermal filler to disappear.

With Hyalase, Hyaluronic acid based dermal fillers that have been placed incorrectly or in excessive amounts, can be dissolved safely and naturally.

What is Hyalase?

Hyalase contains Hyaluronidase which is a naturally occurring enzyme that breaks down Hyaluronic acid.

Both Hyaluronic acid and Hyaluronidase exist naturally in our body.

The body produces hyaluronic acid whilst hyaluronidase is responsible for hyaluronic acid turnover by breaking down hyaluronic acid. Think of them as Yin and Yang.

Majority of dermal fillers contain Hyaluronic acid as the main constituent. Hence, Hyaluronidase is the perfect method for dissolving unwanted dermal fillers.

How is Hyalase administered?

Hyalase is injected using a tiny sharp needle or micro cannula into the targeted treatment area.

Dr Edwin prefers to use the sharp needle for a localized area such as nose / chin while larger areas such as cheeks are best treated using the micro cannula technique.

How long before I see results? What is the duration of treatment?

Results are usually seen within 24 hours of treatment.

Treatment duration for each area is 15 minutes. 

Dr Edwin will schedule a review after 1 week so as to allow time for swelling to subside.

What are the common side effects?

Swelling and bruising is commonly seen after Hyalase injections.

These are temporary and subside after 4 to 7 days.

Allergic reactions have been reported, but these are very rare.

How many sessions do i need?

For most patients, 1 session will be enough. However, if large volumes of dermal fillers are present, a second session may be required to dissolve the filler completely.

Hyalase and Semi-permanent fillers

Unfortunately, Hyalase is only effective when treating Hyaluronic acid based dermal fillers.

Semi-permanent fillers of the following brands can not be dissolved with Hyalase.

  • Radiesse (Calcium Hydroxylapartite) 
  • Ellanse (Polycaprolactone)
  • Sculptra (PLLA)

Speak to us today to find out how you can dissolve unwanted fillers safely and effectively.

Roaccutane Acne Treatment Singapore

Roaccutane – The Miracle Acne cure?

Stubborn acne not improving despite religiously applying skincare products, oral antibiotics or regular facials?

Roaccutane may be the answer to your problems!

What is Roaccutane?

Roaccutane’s main ingredient is Isotretinoin, a derivative of Vitamin A.

Having been in the market since the 1980s, its effects are well studied and is used regularly by skin doctors all over the world to treat moderate to severe acne.

You may have heard of it under different brand names such as Roaccutane, Accutane, Oratane, Acnotin and Nimegen.

How does Roaccutane work?

Roaccutane is currently the single most effective medication available for acne treatment because it is the only medication that can target all 4 causes of Acne Formation.

  • Excessive sebum (oil) production

  • Clogged pores due to abnormal skin turnover

  • Inflammation

  • Bacterial P.acnes proliferation

Other forms of acne treatment such as topical creams, oral antibiotics, facials or lasers can only partially target these factors.

Sounds great! Lets get started!

Not so fast, even though Roaccutane is one of the most effective ways to treat acne, there are some factors to consider.

How long before I see results? What is the duration of treatment?

Roaccutane requires long term commitment.

Studies report that majority of patients can achieve acne clearance after 16 to 20 weeks. Please note that this time frame is dependent on the patient's dosage and body weight.

As such, the treatment duration can range between 4 to 12 months with the goal to achieve a total treatment dose accumulation of 120mg/kg. 

After completing a course of Roaccutane, Acne clearance is usually permanent with some studies reporting less than 3% recurrence risk.

How much should I take? Higher dosage = better?

Previous studies describe the starting dose at 0.5 to 1mg/kg/day. Assuming a body weight of 50kg, that is between 25 to 50mg a day.

Depending on severity, Dr Edwin prefers to start patients at a lower dose of 20mg a day as newer studies show that lower doses in Asians are just as effective AND have lower side effect risks + cost savings.

An expert skin doctor will be able to tailor a treatment course for you.

For example, if you have moderate acne, Dr Edwin may choose to start at an every other day (EOD) dosing instead of a daily dosing to minimise the risk of purging and side effects whilst gradually increasing the dose over several months.

Important Precautions

Roaccutane can lead to birth defects when taken during pregnancy, hence it is of paramount importance that birth control methods be utilized when females are on this medication.

Of note, Roaccutane does not impair fertility and does not reduce your ability to conceive.

Patients who are breastfeeding or have a medical history of Liver or Kidney disease, high blood cholesterol levels or Hypervitaminosis A are also not suitable candidates for Roaccutane treatment.

How long must I stop Roaccutane for if I wish to get pregnant?

It is recommended to stop Roaccutane for at least 1 month before trying to conceive.

What are the common side effects?

Skin dryness

Roaccutane reduces oil and sebum production all over the skin. This manifests most commonly as dry eyes and chapped lips which can be easily remedied with eye drops and lip balm.

Mild joint and muscle aches

Rest assured, for most people, these mild aches are not significant enough to impact your daily routine and exercises.


For the first 4-6 weeks, acne may worsen before they gradually improve.

Do not be demoralized!

To minimise the risk of purging, Dr Edwin has 2 methods. He covers patients with a course of compatible oral antibiotics and prefers to start Roaccutane at a lower dose in the first 2 months with gradual increments over time.

Mood Changes

There have been scattered reports of individuals reporting changes in mood with symptoms suggestive of depression whilst on Roaccutane.

However, to date there is no compelling evidence from studies to suggest a direct link between oral isotretinoin and low mood. Dr Edwin will schedule regular follow ups to monitor for such issues.

Must I stop my facials or laser treatments?

The latest studies report that it is generally safe to continue with facials and lasers and there is no increased risk of poor wound healing ever after ablative laser treatments whilst on Roaccutane.

Dr Edwin will customize a safe and effective treatment plan which will comprise of the following treatment options to hasten the acne treatment and clearance process. 

Speak to us today to find out how you can combat acne and achieve clear skin!

GetProfessional Advice

Book a consultation now with Dr Edwin to learn how your skin goals can be achieved.

Leave us your name, contact details and we will be in touch soon!